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[3] In essence, pyridoxines mechanism of action is to restore or maintain levels of PLP, thereby supporting the enzymatic processes that depend on this cofactor

But if you crank somebody up really high, we dont know, but I speculate we would still get that resistance that I spoke up with insulin resistance

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Other peptides under investigation Several additional peptides are being studied for disc-related applications, though with less established evidence: Vasoactive Intestinal Peptide (VIP) has demonstrated the ability to slow disc degeneration progression and improve aggrecan levels in mouse studies

Since it remains under investigation, its long-term safety and efficacy will require continued scrutiny as more patients experience it and more evidence is accrued